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"The lack of rigorous, long-term studies is a major concern," notes Dr

Retatrutide is an unlicensed triple agonist targeting GLP-1, GIP, and glucagon receptors, currently under clinical investigation for obesity and type 2 diabetes

Still, it carries no legal therapeutic-use status which is why every legitimate source frames it strictly as a research chemical, not a treatment

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Side Effect Profiles Whether semaglutide comes in a pill or injection, the most common side effects are the same: Stomach pain Yellow skin or eyes Fever Sweating Dizziness Anxiety Nausea Bloating Vomiting Constipation Diarrhea Faster heartbeat Shakiness or weakness Headaches Blurred vision Fatigue Interestingly, oral and injectable options have about the same risk of adverse side effects