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Prolonged release melatonin in the treatment of primary insomnia: evaluation of efficacy and safety in older adults

Residual variance was allowed to depend on the hepatic function group

Acosta A, Camilleri M

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Personal or family history of medullary thyroid carcinoma, multiple endocrine neoplasia syndrome type 2, or severe gastrointestinal conditions like gastroparesis may rule out tirzepatide and similar GLP-1 based therapies