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Shorten the cycle if: results have plateaued for 2+ weeks despite dose optimization, you are experiencing fatigue or other signs of potential receptor desensitization, or your goals have been achieved before the planned cycle end

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Conflict of interest Authors LY, CY, YH, FY, and HT were employed by Kweichow Moutai Distillery Co., Ltd

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All ethical approvals were in place before the initiation of studies on humans

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