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Vanderheiden A, Harrison L, Warshauer J, Li X, Adams-Huet B, Lingvay I

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r-sFNDC5 strongly induced the expression of browning-related genes UCP-1, PRDM16, Cidea, and TMEM26 in a dose-dependent manner with the maximal activity at 50 nM, while GLP-1 (10 and 100 nM) showed only a weak browning activity (Figure 5A)

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