Others didn't truly stop obesity treatment at all: More than one-quarter switched to a different weight loss medication, and nearly one in five restarted their original GLP-1 within about six months
While possible, maintaining results after stopping GLP-1 therapy is challenging and requires intensive lifestyle modifications including 200-300 minutes of weekly exercise, consistent dietary changes, regular self-monitoring, and often ongoing behavioral support
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In Europe, the incidence of obesity is five times higher than it was after World War II, and the number of obese people doubles yearly (4)
Both analyses were performed using the same methods as the primary analysis (ESM Tables 68)