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The high insulin resistance commonly found in PCOS patients can have a detrimental effect not only on fat production, also on normal ovulation

There are receptors for GLP-1 in the digestive tract, in the brain, and in the pancreas ( think of receptors as molecular landing pads on the outside of cells where GLP-1 can dock and work its magic )

They handle different problems

Johns Wort while taking this contraceptive can increase the risk of pregnancy

But the total body of evidence is small, and the large independent randomized controlled trial that would cement AHK-Cu's clinical status hasn't been done yet

Despite observing expected processes associated with GLP1R activity, like influence on T2D, hyper- and hypoglycaemia and obesity we observed a plethora of other processes and pathways which could be considered a side effect of GLP1R targeted therapy