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Given these primary effects, it might not make sense how GLP-1s can affect bone density
As of 2022, GLP-1RAs have been recommended as first-line treatments, along with SGLT-2 inhibitors, for patients with T2DM and cardiovascular disease in American Diabetes Associations Standards of Medical Care in Diabetes (248, 249)
Once reconstituted, the solution should be used promptly or aliquoted and stored at -20C to avoid repeated freeze-thaw cycles, which can degrade the compound
Ways to Reduce GLP-1 Costs Without Private Medical Insurance Coverage For patients who do not qualify for NHS prescriptions or lack private medical insurance coverage, several strategies may help reduce the financial burden of GLP-1 therapy whilst maintaining safe and appropriate care