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"It is possible that women using hormone therapy were already engaged in healthier behaviours, or that menopause symptom relief improved sleep and quality of life, making it easier to stay engaged with dietary and physical activity changes." Castaneda explained that while more studies that control for these factors are needed, the findings are clinically meaningful

Patients with a history of cholecystectomy (gallbladder already removed) can generally use weight loss injections with lower gallbladder-specific risk, though other biliary tract complications remain possible

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