In order for your cells to function optimally, they require sufficient delivery of oxygen and nutrients and there is a big interplay between vitamin B12, folate, and iron for erythropoiesis (red blood cell formation) 2
References: Heffernan M, Summers RJ, Thorburn A, Ogru E, Gianello R, Jiang WJ, Ng FM
Research in preclinical models has explored its role in NNMT inhibition, NAD+ metabolism, and cellular energetics (pmc.ncbi.nlm.nih.gov, pubmed.ncbi.nlm.nih.gov)
This list may not include all contraindications
Tesofensine administration on a diet-induced obesity model This study investigated the effectiveness of tesofensine in treating obesity using a diet-induced obesity model [20, 21]
Vegetarian and Vegan Support: Individuals following a vegetarian or vegan lifestyle often struggle to obtain sufficient B12 from diet alone