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The convergence of these pathways at the level of AMPK and SIRT1 underscores their role as master regulators of EAs pleiotropic effects in MASLD (43, 67)

The current consensus among endocrinologists and diabetologists is that there is no evidence of direct bone toxicity with Ozempic when used as directed for its licensed indication

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In rodent models, long-term administration of Epithalon was associated with increased lifespan, reduced tumor incidence, and improved markers of physical function in aged animals

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