Regulatory Toxicology and Pharmacology, 114 , 104665
But is his approach revolutionary or reckless
Lower NAD+ means: Less energy production Slower DNA repair Impaired metabolism Reduced cellular cleanup (autophagy, the process cells use to remove damaged components) Compromised mitochondrial health NAD+ itself cant be absorbed well as a supplement
Preclinical studies have demonstrated that antibiotic treatment induces gut dysbiosis-marked by reduced alpha diversity, a decreased Firmicutes/Bacteroidetes ratio, depletion of beneficial genera, and enrichment of pro-inflammatory taxa (Tejkalov et al., 2023
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