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Journal of the American Medical Association , 294(1), 97104

152 Preclinical studies have suggested that cytokine-driven glial activation may contribute to memory impairment and cognitive decline

The selective vulnerability in females led the authors to hypothesize a role for estrogen-linked mechanisms, although this was not tested

These medications work by stimulating insulin production, lowering glucagon release, and slowing digestion together creating better glucose control and improved stability