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(People with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2 shouldn't take these medications.) GLP-1 agonists also have a risk of causing other rare but dangerous side effects, like pancreatitis and gallbladder disease

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Paul Kolodzik, a 64-year-old metabolic-health specialist and physician from Vandalia, Ohio, about the weight-loss drug semaglutide

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These improvements appear on standard metabolic panels and reflect the medication's core mechanismslowing stomach emptying to prevent rapid glucose spikes after meals