References The following publications are provided for general scientific background regarding dual receptor agonist research
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HbA1c reductions up to 1.6 percentage points Weight trajectory: Weight loss had not plateaued by 52 weeks, indicating potential for further reduction with continued treatment Cardiometabolic: Improvements in waist circumference, blood pressure, hs-CRP, and lipid parameters Evidence level: Moderate -- well-designed phase 2 with NEJM publication, but single trial, no head-to-head comparisons
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HenneyAGillespieCLaiJSchofieldPRileyDCaleyachettyRet al
No single answer covers all scenariosIGF-1 LR3 legal status depends on which regulatory lens applies