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274,276 This indicates that Trx regulates the MMP/TIMP balance by differentially inhibiting the activities of TIMP and MMP, and this process depends on the redox active sites of Trx and TrxR

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The 16S data was tested for normality and alpha-diversity metrics were statistically compared using multiple unpaired t-tests, corrected for multiple comparisons using the HolmSidak method (GraphPad Software Inc., La Jolla, CA)

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