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Homocysteine may also react with nitric oxide in the body to form S-nitrosohomocysteine, a compound that causes endothelial damage and reduces the vasodilatory function of blood vessels.2,21 The primary goal in treating hyperhomocysteinemia is to reduce elevated plasma homocysteine levels in order to minimize the risk of neurological and vascular complications

Issues such as limited bioavailability, metabolic differences, and challenges in dose optimization can impact the efficacy of natural compounds in clinical settings compared to preclinical studies (Oyanna and Clarke 2024)

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Blepharospasm : Involuntary or overactive muscles causing eyelid spasms