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15 16 Sermorelin, under the brand name Geref, was FDA-approved for pediatric growth hormone deficiency but was later taken off the market for non-medical reasons

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The specific protocol used in any individual case depends on the patient's clinical picture and is determined by the provider

Competitive athletes should also be cautious because peptide use may create eligibility or anti-doping issues

This leads to dose-dependent weight loss (typically 8-15% in monotherapy trials), with additive effects when combined with GLP-1 agonists like semaglutide due to complementary mechanisms on energy balance and gastrointestinal function