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PLGA is a hydrophobic polymer, which is more suited to encapsulate hydrophobic rather than hydrophilic agents via two general methods 4 : (1) Nanoprecipitation, in which PLGA and agents to be encapsulated are dissolved in a good solvent and then co-precipitate into nanoparticles upon addition into a non-solvent for both

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Sudden death was sometimes preceded by neurologic signs, vocalization, or collapse

The polar R group is then categorized as uncharged, negatively charged (acidic polar), or positively charged (basic polar)