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Crespel, A., De Boisvilliers, F., Gros, L., Kervran, A

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178,525 FGF2 promotes angiogenesis and retinal fibrosis by stimulating vascular endothelial cell proliferation and inducing VEGF secretion

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Combining microneedling with topical GHK-Cu is a logical protocol you're getting the mechanical stimulation benefit and improving delivery simultaneously