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3.1 BCS Class I: High Solubility, High Permeability 3.1.1 Warfarin Warfarin is an anticoagulant with a narrow therapeutic index, assessed by measurement of the INR

However, its dysregulated activation drives excessive inflammatory responses and host tissue damage, contributing to autoimmune disorders such as AP ( 3.1 Structure of NLRP3 inflammasome The NLRP3 inflammasome is composed of a sensor (NLRP3), an adaptor (ASC