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Surgery is typically reserved for full tears or refractory cases

Force and membrane potential in acetylcholine and potassium contractures of denervated mouse muscles

Their actions on brain insulin signaling, neuroinflammation, oxidative stress, and mitochondrial function likely contribute to improvements in motor and non-motor symptoms, including cognition, mood, and apathy, while maintaining a neutral effect on dyskinesias

They are FDA-approved to provide the exact same clinical relief.

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Common side effects include gastrointestinal symptoms such as nausea, vomiting, diarrhoea, abdominal pain, and decreased appetite