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Cold exposure narrows blood vessels, causing numbness in fingersespecially with Raynauds

Wang YA, Sun Y, Palmer J, Solomides C, Huang L-C, Shyr Y, et al

These approaches, which focus on mitochondrial function, aim to restore organelle homeostasis and delay ovarian functional decline (Table 1)

More interestingly, exogenous copper can promote ferroptotic cell death, but not Cuproptosis, by directly binding to GPX4 and further increasing GPX4 degradation [176]

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357 Exposure to UV light can lead to mtDNA mutations and the accumulation of dysfunctional mitochondria, disrupting collagen homeostasis and driving oxidative stress accumulation