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Temporal and spatial patterns ofc-fos mRNA induced by intravenous interleukin-1: a cascade of non-neuronal cellular activation at the blood-brain barrier

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Fluorescence distribution within the cells of different groups was observed and photographed using a fluorescence microscope (Eclipse Ti-S, Nikon, Tokyo, Japan)

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In this context, our group previously demonstrated that administration of this phytocomplex at doses of 6.25 mg/kg and 25 mg/kg body weight in aged rats significantly reduced neuroinflammatory markers, including TNF-, COX-2, and IL-1, within the dentate gyrus of the hippocampus