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When the body loses weight quickly, especially in the first 48 weeks of treatment, the diaphragm and chest wall experience structural shifts that can feel unusual or cause mild dyspnea during physical activity

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The evidence comes primarily from clinical practice reports and studies examining GLP-1 agonists combined with muscle-protective agents more broadly

Beside effects on lipid metabolism, statins have anti-inflammatory, anti-apoptotic and antioxidant effects [95]