Manganese activates NLRP3 inflammasome signaling and propagates exosomal release of ASC in microglial cells
However, this absorption method occurs only to a limited extent
This relationship can be rationalized by the similar chemical mechanism, involving an aromatic nucleophilic attack by the sulfur of glutathione to form a Meisenheimer -complex, which is followed by the release of the common conjugate S-2,4-dinitrophenylglutathione
Garcia-Ojalvo, J., Sancho, J
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