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GHK-Cu, or copper peptide GHK, is a tripeptide studied for collagen synthesis and cellular repair
31,32 Accordingly, a meta-analysis including 68,653 patients from 10 trials showed that GLP-1 RAs reduce HF hospitalisations only in patients without history of previously diagnosed HF
doi: 10.1080/00365521.2023.2173533 190 LakhanSEKirchgessnerA
However, the glutathione group did demonstrate a trend towards improved forced expiratory volume (FEV1)
Until recently, drugs that directly target renal tubular injury in patients with DKD have been limited
This latter fact indicates that a resistance to the peptide is unlikely to arise and that longer-term treatment would result in even greater weight loss
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