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The data were fully de-identified prior to analysis
Type 2 diabetes mellitus and osteoarthritis
[1] [2] Signs of concern include markedly reduced urine output, swelling, or persistent vomiting/diarrhea
No weight loss medication is universally safe for all kidney conditions, but GLP-1 receptor agonists such as semaglutide are currently among the most studied options and may offer renoprotective benefits in people with type 2 diabetes and CKD, whilst orlistat carries a documented risk of kidney stones and oxalate nephropathy
Peptides can be safer and more targeted in their effects, with fewer side effects than steroids
However, clinical benefit should be assessed by a qualified healthcare provider through biomarkers and symptom monitoring
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