semaglutide pregnancy discontinue 2 months before conception label Could GL-1 Weight Loss Peptides Be Boosting Fertility — and What About Safety? Contraception warning over weight-loss drugs

van Bloemendaal L, RG IJ, Ten Kulve JS, Barkhof F, Konrad RJ, Drent ML et al

Back Illman, J (12-16 Dec 2023) 'Vincent Marks: Obituary', British Medical Journal , 383, 2750

34 They are found in body fluids such as saliva, urine, semen, milk, and blood

Peptides May Be Preferred When: You want to preserve natural testosterone production and HPG axis function Fertility is a current or future concern Testosterone levels are mildly to moderately low (300-500 ng/dL) Symptoms are present but not severely impacting quality of life You prefer a therapy that works with your bodys natural systems You are interested in the additional benefits of GH optimization alongside testosterone support TRT May Be Preferred When: Testosterone levels are severely low (below 250 ng/dL) Symptoms are significantly impacting daily function and quality of life Primary hypogonadism (testicular failure) is the diagnosis, where the testes cannot respond to stimulation Faster and more predictable results from testosterone therapy are clinically important Previous peptide therapy has not produced adequate improvement In some cases, a combined approach using both peptides and TRT may be optimal

2004 Jun;23(2):213-7

Naltrexone-bupropion (Contrave) : This is another combination prescription medication that combines an opioid receptor antagonist (naltrexone) and a dopamine and norepinephrine reuptake inhibitor (bupropion) to help with weight loss