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Beyond this compound, safflower seeds contain serotonin derivatives such as N-(p-Coumaroyl)serotonin and N-Feruloylserotonin, which demonstrate potent free radical scavenging activity and may contribute synergistically to the observed health benefits of safflower oil extracts [3]
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The authors suggest that besides correlated to poor survival, high B7-H3 expression may be correlated to refractoriness to anti-PD-1/programmed death-ligand 1 (PD-L1) immunotherapy by impairing CD8+ T-cell mediated tumor immunity
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