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Further, the model spectra included a macromolecule spectrum acquired from the occipital cortex of 5 volunteers, using an inversion recovery sequence (TR = 3 s, TE = 11 ms, inversion time TI = 0.685 s)
Samples were transferred to Miro5 buffer (pH 7.1, 110 mM sucrose, 60 mM potassium lactobionate, 20 mM taurine, 10 mM monobasic potassium phosphate, 3 mM magnesium chloride, 20 mM HEPES, 0.5 mM EGTA, 1 mg/mL BSA) and washed for 3 10 min on a rocker at 4 C
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Patents for IN delivery of new formulations to the CNS, patents for IN delivery of peptides/proteins to the CNS, patents explaining delivery devices for IN delivery to the CNS, and patents for IN delivery of synthetic drugs to the CNS are some of the types of patents filed on IN delivery to the brain
doi: 10.1038/nrc1894 189 MishchenkoTABalalaevaIVVedunovaMVKryskoDV
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