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The association of TBC1D9B with other proteins and/or lipids, e.g., in response to physiological challenges, such as nutrient stress, may also steer its activity to distinct subcellular sites, e.g., to lysosomes (this study), starvation-induced vesicles 36 , or recycling endosomes 38,52,53 via mechanisms that remain to be explored

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We, therefore, do not discard the hypothesis that the observed effects could be caused by microcrystals of uric acid, non-visualized by laser scanning confocal microscopy combined with reflection microscopy 7 or polarizing microscopy 82

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MiR-375 exerts a multifunctional role as a regulator of the expression of several genes related to lipid metabolism