This dominance is driven by the clinical success and regulatory approval of highly effective therapeutic agents targeting both central and peripheral mechanisms of obesity
2020;7(1):e000370
According to the Saxenda Summary of Product Characteristics, treatment should be discontinued if less than 5% weight loss is achieved after 12 weeks on the maintenance dose of 3.0 mg daily Blood pressure and heart rate : Saxenda can increase heart rate, so cardiovascular parameters should be monitored regularly Blood glucose levels : Particularly important for patients with type 2 diabetes or prediabetes, as weight loss and GLP-1 agonist effects can improve glycaemic control Lipid profile and other metabolic markers : To assess improvement in cardiovascular risk factors Mental health and wellbeing : Weight loss can affect mood, and any concerns about depression or suicidal thoughts should be reported immediately Managing common gastrointestinal side effects involves eating smaller, more frequent meals, avoiding high-fat foods, staying well-hydrated, and allowing time for your body to adjust to each dose increase
Avoid using on bony areas
In direct comparisons of ALC with active drugs, ALC had fewer reported AEs, mostly CNS or GI, while comparator events reflected drug-specific profiles (eg., endocrine events with amisulpride)
[DOI] [PMC free article] [PubMed] [Google Scholar] 15.Frye R.E., Melnyk S., MacFabe D.F
