Recently, clinical trials of tirzepatide, a dual GLP-1R and glucose-dependent insulinotropic polypeptide receptor (GIPR) agonist, have achieved approximately 20% weight loss in substantial proportions of people with obesity (1)
10.1016/j.jcmg.2010.10.008 29 LairB.LaurensC.Van Den BoschB.MoroC
Anwar is with the Department of Dermatology and Venereology, Faculty of Medicine Universitas Hasanuddin, Dr
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Whether depletion of specific key nutrients, including vitamins (eg vitamin D or vitamin K) could result in the specific bone and visceral effects remains unclear from the data we collected in this review
Until then, the notification said GLP-1 RAs should only be prescribed for their licensed indication, and clinicians should avoid initiating people with T2DM on GLP-1 RAs for the duration of the national shortage