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Unlike obesity, which affects both sexes and typically presents with central fat accumulation, lipedema fat is more resistant to weight loss, diet, and bariatric surgery

This is the molecular machinery that allows cells to migrate

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Thyroid hormones, serotonin and mood: of synergy and significance in the adult brain

The thyroid gland is also comprehensively assessed, with tests for TSH, free T3, and T4, as the thyroid, acting as a metabolic regulator, significantly influences energy, weight, and mood

Variants near or overlapping genes such as MALAT1 , involved in gene regulation, SCYL1 , associated with intracellular trafficking, and LTBP3 , part of the TGF- signaling pathway on chromosome 11, along with DENND1A on chromosome 9, which is linked to hormonal regulation and vesicle-mediated transport, suggest mechanisms that jointly influence both disorders [57]