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Dosing Protocols and Administration Due to the short half-life, research protocols typically employ bilateral intramuscular injection into target muscles of 20-100 mcg per injection site, administered immediately post-workout when muscle is primed for growth, multiple times per week (not daily, due to potency), with cycling protocols (e.g., 4-6 weeks on, 4-6 off), and often combined with growth hormone or secretagogues

Xiao H, Jiang Y, He W, Xu D, Chen P, Liu D, et al

One study that followed about 100 patients who were injected once in the knee with hyaluronic acid because of osteoarthritis determined that its effect lasts for a year in most cases, that it is optimally tolerated by patients and that it is completely safe

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Life Sci (2021) 284:119942

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