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Covalent peptide/protein drugs Small molecule covalent drugs have many advantages compared with noncovalent drugs, such as increased biochemical efficiency and potency, improved pharmacokinetics, prolonged duration of action, reduced dosage and dosing frequency, and potent inhibition of intractable targets 264

Prescribing Ozempic and Wegovy for weight loss is associated with an increased risk of erectile dysfunction and hypogonadism in non-diabetic males

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This table summarizes efficacy, cardiovascular, heart failure, renal, safety, cost, and access considerations of major glucose-lowering drug classes in type 2 diabetes mellitus (T2DM)

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Several events seen in the brain of neurodegenerative diseases could give rise to an abnormal production of reactive oxygen spices (ROS)