Table 1, Figure 2), all-cause mortality (12 RCTs
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Collectively, these findings establish PKM2 as a pivotal metabolic checkpoint, whose allosteric regulation offers a compelling strategy for immunomodulation by skewing the balance away from pro-inflammatory Th17 responses and toward Treg cell functions
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Reduction of oxidative stress and inflammation by blunting daily acute glucose fluctuations in patients with type 2 diabetes: role of dipeptidyl peptidase-IV inhibition
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