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doi: 10.1111/j.1471-4159.2010.06919.x 40 DhirSTarasenkoMNapoliEGiuliviC

However, the limitations of animal models, the lack of long-term follow-up data, single-dose experiments (1.2 mg/kg), and the lack of mechanistic studies limit the generalizability and reliability of the results

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