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Pigmented BCC is a subtype with hyperpigmented plaque and nodules and resembles melanoma (Figure 7) (34)

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However, during clinical trials, researchers observed that these medications also led to significant weight loss in many participants, prompting further studies specifically targeting populations with obesity

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NCT04847557) seeks to evaluate the effect of tirzepatide (is a dual agonist for the glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptors) over 52 weeks in 700 patients with heart failure with preserved ejection fraction (HFpEF) and obesity