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First-Pass effect

Answer: Epithalon targets telomere and pineal biology specifically, which sets it apart from broader longevity tools that work mainly on cellular energy, hormones, or inflammation

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Diabet Med 2018;35:306-316 Rytter K, Madsen KP, Andersen HU, Hommel E, Pedersen-Bjergaard U, Schmidt S, et al

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The risk-benefit calculation doesn't support chronic use with current evidence