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IDE-397 is another MAT2A inhibitor with low hepatotoxicity and high solubility that has shown potent modulation of SAM and symmetric dimethyarginine (SDMA) in preclinical studies

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[DOI] [PubMed] [Google Scholar] 73.Angelopoulou R, Lavranos G, Manolakou P

10.1128/jvi.74.13.6021-6030.2000 153 RoudnickyF.KimB