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When oxidative stress occurs, it can lead to inflammation, fibrosis, and even cirrhosis over time

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Gastroenterology 116 : 921935 Acharyya S, Villalta SA, Bakkar N, Bupha-Intr T, Janssen PM, Carathers M, Li ZW, Beg AA, Ghosh S, Sahenk Z, Weinstein M, Gardner KL, Rafael-Fortney JA, Karin M, Tidball JG, Baldwin AS, Guttridge DC 2007 Interplay of IKK/NF-kappaB signaling in macrophages and myofibers promotes muscle degeneration in Duchenne muscular dystrophy

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(jack fruit) leaf extracts: Remarkable attenuations of hyperglycemia and hyperlipidemia in streptozotocin-diabetic rats