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Semaglutide dials down appetite and slows gastric emptying

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A: The starting dose is intended to help the body adjust to the medication and reduce gastrointestinal side effects before increasing to therapeutic doses

doi:10.1056/NEJMcp2009249 3

FDA prescribing information for some GLP-1 receptor agonists (particularly those approved for weight management) includes recommendations to monitor heart rate at regular intervals and consider discontinuation for sustained increases in resting heart rate