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The peptide's ability to cross the blood-brain barrier and its stability may make this route viable

10.1007/s00125-019-05021-6 171

Springer, New Delhi Wang H, Zou Z, Wang S, Gong M (2014) Deep sequencing-based transcriptome analysis of the oil-bearing plant physic Nut (' Jatropha curcas L.) under cold stress

Mechanistically, this was associated with increased expression/internalization of VEGFR2 and activation of downstream Akt-eNOS signaling (Hsieh 2017)