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No blinding was used in the initial mouse study, though the CROs conducting the second mouse study and the NHP study were blinded to the antibodies we supplied
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With decades of expertise in solid-phase peptide synthesis and industrial-scale production infrastructure, Bachem helps pharmaceutical and biotech partners develop scalable processes that support both clinical development and long-term commercial supply
83 suggesting mechanical unloading as a primary contributor
The rationale is straightforward: a 120kg individual has significantly more tissue volume for the peptide to distribute through than a 70kg individual, which affects both the effective concentration at receptor sites and the perceived intensity of side effects
Furthermore, dietary potassium from animal sources (dairy, meats, and soups), highly processed foods, and foods with potassium additives are more likely to have greater impact on potassium level than the potassium from plant-based foods
