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44 In subsequent studies, transgenic mice expressing constitutively active MLCK (CA-MLCK), specifically within the intestinal epithelial cells, demonstrated significant gut permeability in the jejunum (using bovine serum albumin) and the colon (using creatinine and sucralose)

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Here is how the math breaks down for vial usage: Phase 1 (0.25 mg/week for 4 weeks): 7.5 units per week times 4 weeks = 30 units used

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