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The glucagon receptor activation may provide muscle-protective effects beyond other medications in this class, though more research is needed to confirm this observation
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Whilst there is a range of possibilities that would require large-scale investigation, the authors also hypothesize that these discrepancies arise as women are less likely to have insulin abnormalities and are less susceptible to its detrimental effects
This may have set the scene for an adaptive conflict where on one side selection would favour tolerance to a spike in GLP-1 in blood as a result of envenomation and on the other increased potency as a venom component