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This design allowed the controlled release of metabolites, such as urea, while preventing the release of genetically modified cells into host tissues, thus mitigating safety concerns

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doi: 10.1096/fba.2024-00151 Dacquin R, Davey RA, Laplace C, et al

Eli Lilly Eli Lilly and Company announced that Foundayo (orforglipron) is now available to adults with obesity or overweight with weight-related medical problems following the FDA approval on April 1, 2026