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Strikingly, we uncovered the AKT1-PRMT7-GLUD1 axis as a critical controller of tumor growth, providing a potential target and strategy for clinical treatment of gastric cancer

2 It wasnt seen in the Phase 2 trial, so its appearance at higher Phase 3 doses raised questions about what was driving it

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Glucagon is a hormone that stimulates the liver to convert glycogen into glucose, hence raising the concentration of glucose in the blood

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