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As metabolic comorbidities like obesity and diabetes become increasingly prevalent among patients with multiple sclerosis (MS), clinicians face questions about using semaglutide safely in this population

Patients with pre-existing significant hyponatremia, hypokalemia, hypomagnesemia, and/or hypercalcemia should have their electrolyte imbalances corrected before hydrochlorothiazide is initiated

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This stage often builds momentum, but staying consistent and following proper dosage is key

However, an impaired cysteine uptake from the plasma has been proposed secondary to a decrease in plasma GSH

Rotate injection sites to reduce local irritation